Zyban® (Bupropion/Wellbutrin) Overview

Prescription only, tablet form, non-nicotine medication, nicotine cravings are diminished.


Zyban® (Bupropion SR or Wellbutrin SR)

What is Zyban®?

Zyban is a brand name for the drug bupropion hydrochloride. Bupropion hydrochloride, marketed under the names of Zyban®. Wellbutrin® SR and Wellbutrin® XL by GSK (GlaxoSmithKline) is a prescription strength anti-depressant medicine also used to help people quit smoking. Wellbutrin SR and Wellbutrin XL are typically used to treat depression, while Zyban is most often prescribed as a quit smoking aid. Zyban is taken in pill form.

Taking this Medication:

  • Start taking the medication one to two weeks prior to your quit date.
  • Begin with a dose of 150 mg every AM for 3 days, then increase to 150 mg two times a day for the duration of treatment (determined by your doctor).

How does Zyban® Work?

While it isn’t understood exactly how bupropion (Zyban) works, we do know that this prescription strength medicine alters the brain’s chemistry. The result is a reduced interest in smoking. Nicotine cravings are diminished. You should take ZYBAN as directed by your doctor.

Can I Use NRT’s with Zyban®?

Zyban used in conjunction with a NRT can be a good choice for people who have a lot of trouble with nicotine withdrawal. But this should only be done under Doctor’s supervision.

How can I get Zyban®?

Zyban is only available through a prescription. Please talk to your Doctor for more information.

Precautions: Who should not use Zyban®?

Bupropion hydrochloride is not a suitable quit smoking therapy for everyone. Below is a list of conditions under which taking this drug would not be recommended:
  • If you are taking Wellbutrin® SR or Wellbutrin® XL (both are bupropion HCl).
  • If you are taking any other medicine containing bupropion HCl.
  • If you have or have had a seizure disorder.
  • If you have or have had an eating disorder.
  • If you are abruptly discontinuing use of alcohol or sedatives (including benzodiazepines).
  • If you are currently taking or have recently taken a monoamine oxidase inhibitor (MAOI).
  • If you are allergic to bupropion HCl.
  • If you are pregnant or nursing.
  • You should not take this medication if you have an allergic reaction to bupropion.
  • If you have been diagnosed with cardiovascular disease and infrequent reports of hypertension has been reported.

Side Effects:

  • Insomnia
  • Dry Mouth
  • Headaches
  • Change in appetite
  • Agitation
Visit: GlaxoSmithKline for more information on Zyban








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